アメリカの研究で、遺伝子編集を使って高いコレステロール値を下げる新しい方法が発表されました。
A study in the United States has announced a new method to lower high cholesterol levels using gene editing.
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In this study, the CRISPR-Cas9 technology was used.
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This is a technology like scissors that can cut and disable the function of genes.
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Fifteen critically ill patients participated in the study.
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As a result of using the new medication, bad cholesterol LDL decreased by about 50%, and triglycerides decreased by about 55%.
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The current medication can also lower cholesterol, but this treatment may offer long-term effects with just a single session.
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The idea for this treatment was born from the discovery that people with special genes exhibit low cholesterol levels.
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In the study, the function of the ANGPTL3 gene was deactivated.
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In the United States, about one in 250 people has a weaker function of this gene, but there are no health problems.
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Side effects are very minimal, with only slight redness at the injection site or a minor increase in body enzymes, but both recover quickly.
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It is necessary to continue long-term follow-up observation to confirm safety.
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If this treatment is successful, people will no longer need to take medicine every day, and it could help many people.
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We plan to continue the research with an even larger group of people in the future.
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